pentobarbital will lessen the extent or influence of paclitaxel by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unidentified.pentobarbital will reduce the level or result of etoposide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.Use Caution/Monitor. CYP3A4 inducers could improve the me